Hybrid nests are nests that hybrids were going to be born in. Abigail created several nests and spread them across the world
The nest here is shown many times and has been visited by several characters including Logan and Jackson. This nest was blown to pieces by the C4 explosives a team had put in there. The spores from this nest were carried south due to wind patterns. They eventually reached the international airport and trapped the team inside their plane for several hours.